graphic software prism 5.20 (GraphPad Software Inc)
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GraphPad Software Inc
graphic software prism 5.20
Graphic Software Prism 5.20, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/graphic+software+prism+5%2E20/graphic+software+prism+5+20/pm22847705-94-8-12
Average 90 stars, based on 1 article reviews
Graphic Software Prism 5.20, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/graphic+software+prism+5%2E20/graphic+software+prism+5+20/pm22847705-94-8-12
Average 90 stars, based on 1 article reviews
graphic software prism 5.20 - by Bioz Stars,
2026-10
90/100 stars
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Construct:Article Title: Development of liquid chromatography/mass spectrometry based screening assay for PfTrxR inhibitors using relative quantitation of intact thioredoxin. Article Snippet: RATIONALE: Plasmodium falciparum (Pf) thioredoxin reductase (TrxR) catalyzes the reduction of thioredoxin disulfide (Trx–S2) to thioredoxin dithiol (Trx–(SH)2) that is essential for antioxidant defense mechanism and DNA synthesis in the parasite and is a validated drug target for new antimalarial agents.. METHODS: In this study, we have developed a liquid chromatography/mass spectrometry (LC/MS)-based functional assay to identify inhibitors of PfTrxR by quantifying the product formed (Trx–(SH)2) in the enzymatic reaction.. Relative quantitation of the reaction product (intact Trx–(SH)2) was carried out using an Agilent 6520 QTOF mass spectrometer equipped with a positive mode electrospray ionization (ESI) source. Software:Article Title: Development of liquid chromatography/mass spectrometry based screening assay for PfTrxR inhibitors using relative quantitation of intact thioredoxin. Article Snippet: RATIONALE: Plasmodium falciparum (Pf) thioredoxin reductase (TrxR) catalyzes the reduction of thioredoxin disulfide (Trx–S2) to thioredoxin dithiol (Trx–(SH)2) that is essential for antioxidant defense mechanism and DNA synthesis in the parasite and is a validated drug target for new antimalarial agents.. METHODS: In this study, we have developed a liquid chromatography/mass spectrometry (LC/MS)-based functional assay to identify inhibitors of PfTrxR by quantifying the product formed (Trx–(SH)2) in the enzymatic reaction.. Relative quantitation of the reaction product (intact Trx–(SH)2) was carried out using an Agilent 6520 QTOF mass spectrometer equipped with a positive mode electrospray ionization (ESI) source. |